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Figure 4 Effects of Sirolimus on Membrane Association of Soluble NADPH Oxidase Subunits

Effects of sirolimus on membrane association of the soluble NADPH oxidase subunits p67^phox, p47^phox, and rac1. (A) Immunoblotting analysis of indicated subunits in the membrane fraction with densimetric quantification and (B) original blots. *p = 0.005 versus Ctr; n = 5 to 7 animals per group. Cyt = cystolic fraction; Mem = membrane fraction; NADPH = nicotinamide adenosine dinucleotide phosphate; other abbreviations as in Figure 3.