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Figure 4 Amyloid Staining in Advanced Human Atherosclerosis

Advanced human atherosclerotic plaques in the aorta reacting with antiserum to apolipoprotein A-1 (A and C) (bar = 50 µm) in colocalization with amyloid, which was visualized as green birefringence by Congo red staining (B and D). Images used with permission of John Wiley & Sons (33). Hematoxylin-eosin staining of an advanced carotid atherosclerotic plaque (E), exhibiting green birefringence by Congo red staining as an indicator of amyloid deposition in areas near the shoulder (F) and the lipid core (G) in the absence of primary amyloidosis (original magnifications: E: x2; F, G: x5).