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Figure 4 Demonstration of the Main Principle of Our New Hybrid Therapy Ex Vivo

(A) The patch delivery device is put on a piece of muscular septum. (B and C) Fixation of a mini Nitinol anchor on the muscular septum with the custom-designed stapler. (D) Fixation of the patch with 7 mini Nitinol anchors. (E) After releasing the sutures the Nitinol frame detaches from the patch. (F) The patch remains with the mini Nitinol anchors in the muscular septum.