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Figure 3 Effects of Plant Sterols on Atherosclerotic Lesions in ApoE–/– Mice

Atherosclerotic lesion formation was quantitated in the aortic sinus of ApoE–/– mice treated with high-cholesterol WTD or NC supplemented with PSE, EZE, and their combination (PSE + EZE). (A and B) Representative examples, and (C and D) histomorphologic analysis. #p < 0.05 compared with WTD or NC; *p < 0.05 for WTD + EZE versus WTD + PSE or NC + EZE versus NC + PSE; values are mean ± SEM (n = 10/group). Abbreviations as in Figures 1 and 2.