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Figure 2 Macrophage Infiltration in the Infarcted Myocardium

(A to C) Mac-2 immunohistochemistry identified macrophages in young mouse infarcts after 24 h (A), 72 h (B), and 7 days (C) of reperfusion. Density of Mac-2 positive cells peaked after 72 h of reperfusion. (D to F) Macrophage staining in senescent mouse infarcts after 24 h (D), 72 h (E), and 7 days (F) of reperfusion. (G) Comparison of macrophage density in senescent and young mouse infarcts (*p < 0.05 vs. young).