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Figure 2 Echocardiogram in Infarcted Rats

Representative M-mode image reveals a hypokinetic-to-akinetic anterior wall and left ventricular (LV) dilation in the infarcted hearts (B to J) in contrast to normal anterior wall motion in sham-operated heart (A). There are markedly dilated LV end-diastolic diameter and LV end-systolic diameter in groups treated with vehicle (B), Glib (E), Nic + Glib (F), and Pin + Glib (G) compared with those in groups treated with Nic (C) and Pin (D). Besides, infarcted rats treated with Rap (H), Rap + Nic (I), and Rap + Pin (J) showed a significant decrease of LV end-diastolic diameter and LV end-systolic diameter compared with vehicle. IVS = interventricular septum thickness; other abbreviations as in Figure 1.