JACC -- Sluimer et al. 51 (13): 1258 Figure IG6

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Figure 6 Localization of HIF1 ${alpha}$ and HIF2 ${alpha}$ mRNA in Advanced Carotid Lesion

(A) Bright field images of human carotid with an advanced atherosclerotic plaque corresponding to dark field images (B and C). Expression of HIF1 ${alpha}$ (B) and HIF2 ${alpha}$ (C) messenger ribonucleic acid (mRNA) (white dots) was observed in macrophages surrounding the core and in the shoulder regions of advanced atherosclerosis. (D) No signal is observed using sense probes (negative control) for HIF1 ${alpha}$ . Abbreviations as in Figures 1 and 2.