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Figure 2 Differences in Time Constant of Isovolumic Relaxation

Both study groups had no discernable difference in diastolic function at the time of gene transfer. Over the course of the next 2 months after gene transfer, there was a clear trend favoring the SERCA2a group for lack of deterioration of diastolic function. This confirms a potential positive effect on LV lusitropy of SERCA2a overexpression. Tau = time constant of isovolumic relaxation; other abbreviations as in Figure 1.