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Figure 2 Percent Inhibition of Late Aggregation

Late platelet aggregation: 6 min after the addition of the agonist. Group A, clopidogrel 300 mg the day before (15 h) + 75 mg the morning of the interventional procedure; Group B, clopidogrel 600 mg the morning of (2 h before) the interventional procedure; Group C, clopidogrel 600 mg the day before (15 h) and 600 mg the morning of (2 h before) the interventional procedure. Significant differences between Groups A versus C and Groups B versus C were found for both for 5 and 20 µmol/l adenosine diphosphate (ADP) (see text for details).