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Figure 2 Plasma Ketone Concentrations Before and After Intervention

Ketone concentration at baseline and after 8 and 24 weeks of energy restriction with an VLCHF diet (n = 45) or an HCLF diet (n = 43). *Significant time by diet interaction between the groups (P<0.001) by repeated measures analysis of variance. p < 0.001, p = 0.01 significantly greater than HCLF by post-hoc comparisons at each time point with Bonferonni adjustment for 3 comparisons. Abbreviations as in Figure 1.