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Figure 4 Quantifications of Response to Proarrhythmic Challenge

Arrhythmogenic outcome is depicted for CAVB and high-septal pacing (HSP) dogs. (A) Number of dogs with reproducible TdP relative to group size. Actual numbers indicated in bars (p = NS, Fisher exact test). (B) Mean number of TdP per inducible dog in each group. (C) Mean cumulative durations of TdP within inducible dogs. (D) Mean number of defibrillations necessary to terminate arrhythmias. Mann-Whitney U tests were used for statistical testing in B, C, and D. *p < 0.05 versus CAVB. Note that HSP dogs show less proarrhythmia than CAVB dogs. Abbreviations as in Figures 1 and 2.