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Figure 5 T15 Antibodies and Cell Infiltrates in Lesions of PC-Immunized Mice

Representative micrograph showing immunohistochemistry from atherosclerotic lesions of phosphorylcholine (PC)-immunized apolipoprotein E knockout mice. T lymphocytes were detected using an anti-CD3 antibody, B cells with an anti-CD19 antibody, MHC II⁺ cells with an anti–I-A^b antibody, and T15 antibodies deposited in the lesions with the F6 anti-T15 antiidiotypic antibody (a kind gift from Dr. John Kearney, University of Alabama, Birmingham). Positive cells are stained red (hematoxyilin counterstaining). Original magnification x200. A = adventitia; L = lumen.