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Figure 6 Incorporation of MCP-1 Into a Multiple Biomarker Panel

Unadjusted association between the number of elevated biomarkers (monocyte chemoattractant protein [MCP]-1, brain natriuretic peptide [BNP], and C-reactive protein [CRP]) at baseline (A) and at 4 months (B) and subsequent mortality. An MCP-1 elevation was defined as >238 pg/ml, and BNP elevation as >80 pg/ml; CRP elevation at baseline was defined as >15 mg/l and at 4 months as >3 mg/l. Multivariable adjustment is shown at the bottom of each panel using variables described in the text. HR = hazard ratio.