Click on image to view larger version.

Figure 5 Suppression of Platelet Aggregation by AZD6140 in Clopidogrel-Pretreated Patients

Mean percentage platelet aggregation derived from final aggregation response at 6 min after addition of adenosine diphosphate 20 µmol/l, for clopidogrel-pretreated patients before and after either clopidogrel 75 mg (n = 12) or the first dose of AZD6140 90 mg (n = 9), AZD6140 180 mg (n = 7), or AZD6140 270 mg (n = 16). Error bars show standard deviation and points are nudged on the X axis only to reveal error bars. *p < 0.05 for AZD6140 versus clopidogrel.