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Figure 3 Receiver-Operating Characteristic Curves for Individual Dyssynchrony Methods and the Combined Method

The comparison with the 2-site tissue Doppler longitudinal dyssynchrony data appears on the left, and the comparison with radial dyssynchrony by speckle-tracking radial strain appears on the right. The areas under the curves (AUCs) were significantly greater with the combined approach than with either individual approach and support its favorable ability to predict ejection fraction response to cardiac resynchronization therapy. Sensitivities and specificities were 72% and 77% for the 2-site tissue Doppler method, 84% and 73% for the radial strain method, and 88% and 80% for the combined method. Blue dashed lines = individual dyssynchrony methods; red solid lines = combined method.