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Figure 5 Histopathological Analysis of the Infarcted Mice Hearts

(A) Hematoxylin/eosin picture of the infarcted heart injected with AdPDI/GFP: the area of the wall of the left ventricle affected by the infarct is indicated by a box (original magnification x10). (B) Hematoxylin/eosin picture of the infarcted heart injected with AdPDI/GFP: the involvement of the wall in terms of thickness is indicated by a heavy black line (original magnification x20). (C) Hematoxylin/eosin picture of the infarcted heart injected with Adnull/GFP: the area of the wall of the left ventricle interested by the infarct is indicated by a box (original magnification x10). (D) Hematoxylin/eosin picture of the infarcted heart injected with the vector alone: the involvement of the wall in terms of thickness is indicated by a bold line (original magnification x20). (E) Examples of TUNEL staining in the infarcted hearts injected with AdPDI/GFP and with Adnull/GFP (original magnification x40). (F) Examples of the double staining TUNEL-muscle actin to detect only the apoptotic cardiomyocytes (original magnification x40). Abbreviations as in Figure 1.