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Figure 1 Absolute 35-Day Mortality Versus Fibrinolytic Treatment Delay*

*Solid circles = information from trials included in Fibrinolytic Therapy Trialists’ Collaborative Group analysis; open circles = information from additional trials; small squares = data beyond scale of x/y cross. The linear and nonlinear regression lines are fitted within these data, weighted by inverse of the variance of the absolute benefit in each datapoint. Solid squares = average effects in 6 time-to-treatment groups (areas of squares inversely proportional to variance of absolute benefit described). Reproduced with permission from Boersma et al. (28).