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Figure 5 LDL-C Versus Coronary Plaque Progression/Regression

(Left) First demonstration of the positive correlation between coronary plaque progression by intravascular ultrasound and LDL-C levels in an observational study. Modified from von Birgelen et al. (33). (Right) Confirmation of the relation between LDL-C and coronary plaque progression by data derived from various large randomized trials. Modified from Nissen SE et al. (36). LDL-C = low-density lipoprotein cholesterol; P&M = plaque and media.