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Figure 3 Indexes of LV Systolic Function in Age-Matched Sham and ACF Rats

Left ventricular (LV) function in ACF (open circles) at 12 h; 2 and 5 days; and 4, 8, and 15 weeks compared with age-matched shams (closed circles). Left ventricular end-systolic (LVES) pressure (A), left ventricular end-systolic dimension (LVESD) (B), LV fractional shortening (FS) (C), LVES wall stress () (D), and LV velocity of circumferential shortening (VCF_r) (E). Alternating black and white boxes each represent one 24-h period. Data are presented as mean ± SEM, n values given in Table 1 except: 4-week sham LVESD, LV fractional shortening, and LV VCF_r (n = 9); 8-week sham LVESD, LV fractional shortening, and LV VCF_r (n = 8). *p < 0.008 (= 0.05/6) sham versus ACF at each of the 6 time points. Analyses for left ventricular end-systolic pressure (LVESP), LVESD, and LVVCFr were based on their ranks, whereas analyses for LV fractional shortening and LVES were based on their natural logarithms.