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Figure 3 Apoptotic Properties of Inflammatory Cells in the Bronchovascular Area in Reversible PHT or Irreversible PHT

In irreversible pulmonary hypertension (PHT) the antiapoptotic protein Bcl-2 (A) is strongly expressed by inflammatory cells, whereas immunostaining for apoptotic markers is very low. The proapoptotic proteins caspase-3 (B) and p-53 (C) are strongly expressed by inflammatory cells in reversible PHT.