Click on image to view larger version.

Figure 2 Time Course of SCr Response

Mean change from baseline in postoperative (post-op) serum creatinine (SCr) values over the course of the hospital stay in nesiritide (solid line) and placebo (dotted line) patients. Vertical lines signify 1 SEM. *p < 0.05 nesiritide versus placebo on the basis of longitudinal repeated measures analysis of variance model; p < 0.05 change from baseline on the basis of paired t test. ICU = intensive care unit.