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Figure 1 Primary Efficacy and Safety End Points

(A) Mean weight loss in kilograms; (B) mean dyspnea score (from 1 = markedly worse to 7 = markedly better) at 48 h after randomization in the ultrafiltration (blue circles) and standard-care (red circles) groups; p values are for the comparison between ultrafiltration and standard care. Error bars indicate 95% confidence intervals (CIs). (C) Mean changes from baseline serum creatinine levels at 8, 24, 48, and 72 h after randomization; at discharge; and 10, 30, and 90 days in the ultrafiltration (red bars) and standard-care (blue bars) groups. Error bars indicate 95% CIs. Differences between groups at each time point were evaluated with the Wilcoxon’s rank-sum test; p > 0.05 at all time points for the comparison of mean change in serum creatinine levels between groups.