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Figure 1 Flowchart of the Study, Randomization, and Definition of the 3 Groups

To avoid bias, randomization was performed before the physiologic measurement (see text). DEFER = deferral of percutaneous coronary intervention; FFR = fractional flow reserve; PCI = percutaneous coronary intervention; PERFORM = performance of percutaneous coronary intervention; REFERENCE = percutaneous coronary intervention anyway because of ischemic fractional flow reserve.