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Figure 5 Olmesartan Decreases the Number of Myofibroblasts in the Aortic Valve

Immunostaining for alpha-smooth muscle actin (black) in sections of aortic valve from control (A), hypercholesterolemic (B), and hypercholesterolemic olmesartan-treated (C) rabbits. Sections are counterstained with methyl green. Arrowheads indicate aortic side of valve leaflet. (D) Quantitation of alpha-smooth muscle-stained area corrected for total area. Ao = aorta. Bar = 200 µm.