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Figure 3 Olmesartan Preserves Endothelial Integrity of the Aortic Valve

CD31 immunostaining of aortic valve endothelium from control (A), hypercholesterolemic (B), and hypercholesterolemic olmesartan-treated (C) rabbits. Positive staining is shown as red. Arrowheads indicate aortic side of valve leaflet. (D) Quantitation of CD31-positive circumference corrected for valve surface (on each side of valve). Bar = 200 µm. A = olmesartan; Ao = aorta; C = control; V = vehicle.