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Figure 3 Heterogeneity of Vagal-Induced ERP Shortening Within the PV, PLA, and LAA Corresponds With Heterogeneity of IKAch Distribution Within Each Region

(A) The panel shows heterogeneity of ERP shortening among individual pacing electrodes in the PV, PLA, and LAA. Interelectrode heterogeneity (Variance/N) is the greatest in the PLA and is least in the LAA. Panels B and C show examples of immunostaining (10x magnification) for Kir3.1 in the LAA and PLA, respectively. The Kir3.1 is stained red. In the LAA (B), Kir3.1 staining is very homogeneous. In contrast, staining for Kir3.1 is significantly more heterogeneous in the PLA (C). The black arrows indicate the heterogeneity of red staining in the PLA. Abbreviations as in Figure 1.