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Figure 3 Time Course of Mean SBP and DBP Change in the Placebo and FDC I/H Groups

Note that blood pressure decreased in the active treatment group soon after starting treatment, with no further change in blood pressure over time. The p values compare changes between treatment groups: *p < 0.05; **p < 0.01. DBP = diastolic blood pressure; FDC I/H = fixed-dose combination of isosorbide dinitrate and hydralazine; SBP = systolic blood pressure.