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Figure 1 Early-onset coronary artery disease (CAD) definition criteria in the ADVANCE Study. CABG = coronary artery bypass graft; CK-MB = creatine kinase-MB fraction; CPT = current procedural terminology; EKG = electrocardiogram; ICD-9 = ninth revision of the International Classification of Diseases; MD = metabolic syndrome; PCI = percutaneous coronary intervention.