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Figure 6 Hemodynamic responses to the application of 15 µg inhaled treprostinil. The inhalation time was minimized by increasing treprostinil concentration. A pulse of aerosol was generated every 6 s. Treprostinil aerosol was inhaled in concentrations of 100 µg/ml (18 pulses; n = 6), 200 µg/ml (9 pulses; n = 6), 600 µg/ml (3 pulses; n = 21), 1,000 µg/ml (2 pulses; n = 7), and 2,000 µg/ml (1 pulse; n = 8). Placebo data correspond to Figure 4. Data are shown as mean ± 95% confidence interval. Abbreviations as in Table 1.