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Figure 4 Pharmacodynamics after treprostinil inhalation versus placebo. Placebo or treprostinil in doses of 30, 60, or 90 µg were inhaled (mean ± 95% confidence interval). Maximal decrease of pulmonary vascular resistance (PVR) was comparable for all doses. The duration of pulmonary vasodilation (PVR decrease) seemed to be dose dependent. Abbreviations as in Table 1.