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Figure 4 Photomicraphs showing staining and localization of neutrophil-activating peptide-2, CXCR1, and CXCR2 in thrombus material removed from the site of plaque rupture in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention. Thrombus material stained with omission of the primary antibody as control demonstrated no immunostaining of any of the cellular elements (A). Fairly strong immunostaining of neutrophil-activating peptide-2 (B), CXCR1 (C), and CXCR2 (D) was seen in monocytes (arrows) and in areas with platelets (*). (E) Demonstrates thrombus material with CD41-positive platelets, and (F) demonstrates calprotecin-positive monocytes. Original magnification x 400.