Click on image to view larger version.
Figure 4 (A) Odds ratios for death within 90 days with fibrinolysis-facilitated percutaneous coronary intervention (PCI) versus primary PCI alone. Facilitated PCI had no significant impact on mortality. Overall odds ratios 1.30; 95% confidence interval (CI), 0.92 to 1.83; p = 0.13. The analysis for heterogeneity was nonsignificant (p = 0.46). (B) Odds ratios for reinfarction within 90 days with fibrinolysis-facilitated PCI versus primary PCI alone. Facilitated PCI led to a significant increase in reinfarction. Overall odd ratios, 1.68; 95% CI, 1.12 to 2.51; p = 0.013. The analysis for heterogeneity was nonsignificant (p = 0.46). ASSENT = Assessment of the Safety and Efficacy of a New Treatment Strategy for Acute Myocardial Infarction; PACT = Plasminogen Activator-Angioplasty Compatibility Trial; GRACIA-2 = Primary Optimal Percutaneous Coronary Intervention versus Facilitated Intervention in STEMI patients; MA = meta-analysis; PRAGUE = PRimary Angioplasty in patients transferred from General community hospitals to specialized PTCA Units with or without Emergency thrombolysis.