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Figure 1 Relative risk of all-cause mortality for early invasive therapy compared with conservative therapy at a mean follow-up of 2 years. The results show a long-term survival benefit from early invasive therapy. CI = confidence interval; FRISC-II = Fragmin and Fast Revascularization During Instability in Coronary Disease; ICTUS = Invasive Versus Conservative Treatment in Unstable Coronary Syndromes Investigators; ISAR-COOL = Intracoronary Stenting With Antithrombotic Regimen Cooling Off; RITA-3 = Randomized Intervention Trial of Unstable Angina; RR = relative risk; TIMI-18 = Thrombolysis In Myocardial Infarction-18; TRUCS = Treatment of Refractory Unstable Angina in Geographically Isolated Areas Without Cardiac Surgery; VINO = Value of First Day Coronary Angiography/Angioplasty in Evolving NonST-Segment Elevation Myocardial Infarction.