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Figure 3 Representative scintigraphic images of the experimental and control hands at 1 and 4 h after reperfusion in preconditioned subjects pre-treated with caffeine (A) and saline (B). Annexin targeting was 2% and 3% after saline administration (saline-ischemic preconditioning-ischemic exercise) and 19% and 27% after caffeine administration (caffeine-ischemic preconditioning-ischemic exercise) at 1 and 4 h, respectively.