Click on image to view larger version.

Figure 4 Original beat-by-beat tracings of finger blood pressure (BP) (upper tracings) and heart rate (HR) (lower tracings) in a representative subject on placebo (left) and on norepinephrine reuptake transporter (NET) inhibition with reboxetine (right). On placebo, the patient experienced a typical neurally mediated pre-syncope with a sudden decrease in HR and BP after 24 min of head-up tilt (asterisk). On NET inhibition, upright HR was markedly increased. The subject was able to complete the tilt protocol (42 min) without pre-syncope. bpm = beats/min.