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Figure 3 (A) Multi-detector computed tomography scan of representative myocardial infarcts at weeks 1 and 8 after stem cell injection. As indicated by the arrows, both infarct zones are characterized by the presence of a rim of myocardial tissue on their endocardial surface. However, the thickness of this rim progressively increases in mesenchymal stem cell (MSC)-treated animals and remains unchanged in control subjects. (B) Representative pathology specimens from control and MSC-treated animals confirm increased sub-endocardial rim thickness in the treated animals.