Click on image to view larger version.

Figure 2 Uptake of tracers of myocardial reporter gene expression and perfusion in regions of adenoviral gene transfer (Ad_Tk-VEGF [n = 8]; Ad_VEGF [n = 4]; Ad_sr39tk [n = 4]; remote [n = 8]). (A) Regional uptake of the reporter probe [¹⁸F]fluoro-hydroxymethylbutyl-guanine (FHBG). *p < 0.01 vs. Ad_VEGF and remote. (B) Regional uptake of the perfusion tracer [¹³N]ammonia at rest. *p < 0.01 vs. Ad_sr39tk and remote. (C) [¹³N]ammonia uptake during adenosine vasodilation. *p < 0.01 vs. Ad_sr39tk and remote). Bars indicate mean ± SD.