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Figure 1 Principle of the intravascular elastography measurement procedure. An intravascular ultrasound (IVUS) image is acquired with a low (P₂) and a high (P₁) intraluminal pressure. Using cross-correlation analysis on the high-frequency radiofrequency data, the radial strain in the tissue is determined. This information is superimposed on the IVUS image. In this example, an eccentric soft lesion is visible between the 6- and 12-o’clock positions in the elastogram where it cannot be identified from the IVUS image.