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Figure 4 (Top) A set of in vivo spin echo images was reformatted to display a long-axis view of a diseased aorta from a hypercholesterolemic rabbit model. Orientation is from renal artery level (left) to diaphragm (right) and at single transverse slices (bottom) before (pre) and 120 min after (post) infusion of vß3-integrin targeted gadolinium-carrying perfluorocarbon nanoparticles. Semiautomated segmentation (segmented, grayish ring, panel 3) and color-coded signal enhancement (enhancement) above baseline (in percent) are shown. Reprinted, with permission, from Winter et al. (37).