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Figure 4 Representative examples of in vivo Wavelet analysis of radiofrequency (RF) intravascular ultrasound (IVUS) signals from a lipid-laden plaque (A) and from a fibrous plaque without a lipid core (B). The left panel shows conventional IVUS images, the middle panel, the results of Wavelet analysis, the right panel, histologic cross section of the corresponding directional coronary atherectomy specimen with Hematoxylin-Eosin and Azan stains. A similar pattern of color mapping was observed from the RF signal vector of a lipid-laden plaque as seen in the in vitro study. Reprinted with permission from Murashige et al. (30).