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Figure 3 Representative examples of in vitro Wavelet analysis of radiofrequency (RF) intravascular ultrasound (IVUS) signals from a lipid-laden plaque (A) and from a fibrous plaque without a lipid core (B). The upper panel shows RF signals, the middle panel, the results of Wavelet analysis, and the lower panel, histologic specimen of the corresponding arterial cross-section with Masson’s trichrome. In the time-scale domain color-coded mapping of Wavelet analysis, an apparently different pattern of pink area from an RF signal vector of a lipid-laden plaque is observed between scale 20 and scale 30, compared with the fibrous plaque. F = fibrous area; L = lipid core. Reprinted with permission from Murashige et al. (30).