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Figure 2 Kaplan-Meier curves of the occurrence of the primary combined end point of death, myocardial infarction (MI), and urgent target vessel revascularization (UTVR) in patients randomized to placebo, patients randomized to receive a 300-mg loading dose of clopidogrel that was initiated 15 h before percutaneous coronary intervention, and patients randomized to receive a 300-mg loading dose of clopidogrel that was initiated 15 h before percutaneous coronary intervention. For pre-treatment 15 h versus placebo, p = 0.018; for pre-treatment 15 h versus <15 h, p = 0.033; and for placebo versus pre-treatment <15 h, p = 0.72.