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Figure 2 Serum concentrations of (A) N-terminal proatriopeptide (S-ANPN) and (B) N-terminal brain natriuretic peptide (S-proBNP) measured at baseline, 1 day, and 6 months after patent ductus arteriosus (PDA) closure in the whole PDA group and in patients with normal-sized left ventricle (LV) at baseline and in control subjects. _*p < 0.05, p < 0.01, p < 0.001 as compared with control group; p < 0.05, ¶p < 0.01 within PDA group as compared with baseline.