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Figure 2 Left ventricular (LV) function in isolated ejecting hearts from wild-type (WT) and Nox2^–/– mice across a range of LV end-diastolic volumes (EDV). Changes in A and D: maximum rate of rise of LV pressure (LVdP/dt_max); changes in B and E: maximum rate of fall of LV pressure (LVdP/dt_min); changes in C and F: stroke work (SW). Data are mean ± SEM from eight animals. *p < 0.05 banded (solid squares) versus sham (open squares).