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Figure 1 Effect of pressure overload on cardiac fibrosis. (A) Interstitial collagen assessed in left ventricular (LV) sections stained with Picrosirius red. (B to D) messenger ribonuclerc acid expression of procollagen I, procollagen III, and fibronectin. Data are mean ± SEM from six animals. *p < 0.05 versus corresponding sham; p < 0.05 versus banded Nox2^–/–. WT = wild type.