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Figure 4 Simple linear regression is demonstrated with endothelium-dependent vasodilation as the dependent variable and cholesterol high-density lipoprotein (HDL) and systolic blood pressure (BP) as independent variables in subjects with a family history of diabetes (FH+) and subjects without a family history of diabetes (FH–). Individual data are presented for FH+ (solid circles) and FH– (open circles). Positive family history subjects demonstrate blunted endothelial dilation across the range of cholesterol and systolic pressure.