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Figure 1 Graphs showing linear regression between pregnancy-associated protein-A (PAPP-A) score versus plaque thickness (A) and PAPP-A score versus total cells’ plaque cap inflammatory infiltrate (B) for the 65 carotid atherosclerotic plaques submitted to histopathologic examination. A decrease in cap thickness and an increase in inflammatory infiltrate in the cap region of the plaque are both strongly correlated with increase in PAPP-A expression.