Click on image to view larger version.

Figure 3 Effects of time (5 to 40 min), dose (0.1 mmol/kg vs. 0.2 mmol/kg), and inversion time (TI) (adjusted vs. fixed) on infarct size measurements (magnetic resonance imaging [MRI]/ triphenyltetrazolium chloride [TTC] ratio). Using an adjusted TI, infarct size is independent of dose and time within the tested limits. Using a fixed TI, however, infarct size becomes a function of dose and time.