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Figure 2 Collateral conductance measurements for the total tissue mass that depends on the collateral network seven days after femoral artery ligation (open bars). Aspirin treatment significantly reduced collateral conductance, whereas clopidogrel treatment did not functionally affect arteriogenesis (saline: 50.7 ± 1.9 ml/min/100 mm Hg; clopidogrel: 49.5 ± 2.4 ml/min/100 mm Hg; aspirin: 32.6 ± 1.6 ml/min/100 mm Hg). The contralateral hind limb that was subjected to acute occlusion of the femoral artery served as an internal control (solid bars).