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Figure 2 Relation of gender to overall hypertrophic cardiomyopathy (HCM)-related mortality (left panel) and progression to New York Heart Association (NYHA) functional classes III and IV, or heart failure (HF) or stroke death (right panel). Hazard plot based on multivariate Cox regression analysis including age, NYHA functional class, and left ventricular outflow obstruction (gradient 30 mm Hg at rest) at initial evaluation. *Patients who were already in NYHA functional classes III to IV at first evaluation were excluded from this analysis.